Factors associated with short-course antiretroviral prophylaxis (dual therapy) adherence for PMTCT in Nkangala district, South Africa
If you would like to obtain a copy of this Research Output, please contact Hanlie Baudin at firstname.lastname@example.org.
Aim: To identify factors that influence adherence to short-course antiretroviral (ARV) prophylaxis by pregnant women and mothers participating in the HIV prevention of mother to child (PMTCT) programme.
Methods: The sample interviewed included 139 HIV-positive antenatal women 5 (mean gestational age 32 weeks; STD = 2.8, range 4-9 months) and 607 postnatal HIV-positive women, with either having an infant aged 1-10 weeks (30.8%), 11 weeks to
6 months (36.7%) or 7-12 months (32.5%) from Nkangala district, Mpumalanga province, South Africa.
Results: A large percentage of antenatal and postnatal women in this study initiated 6 ARV prophylaxis for PMTCT or were on ART (85.6% and 98%, respectively). Sixty-one per cent of antenatal and 85.9% of postnatal women reported complete adherence to the
appropriate medication schedule in the 4 days preceding the interview or prior to delivery. In multivariate analysis, it was found that women with higher HIV status disclosure and less discrimination were better in maternal AZT adherence, women with higher male
involvement were better in maternal and infant nevirapine adherence.
Conclusion: Adherence to maternal and infant dual therapy prophylaxis was found to be less than optimal. Community factors (discrimination, HIV disclosure, male involvement) contribute to adherence to short-course ARV prophylaxis in this largely rural setting
in South Africa.
Related Research Outputs:
- Determinants of adherence to a single-dose nevirapine regimen for the Prevention of Mother-to-Child HIV Transmission in Gert Sibande district in South Africa
- Programme to improve implementation of the Prevention of Mother to Child Transmission of HIV in Gert Sibande district in Mpumalanga, South Africa: baseline report: Gert Sibande PMTCT programme implementation
- Factors determining prenatal HIV testing for prevention of Mother to Child Transmission of HIV in Mpumalanga, South Africa
- Implementing a rural programme of Prevention of Mother-to-Child Transmission of HIV in Nkangala, South Africa: a baseline evaluation
- Factors influencing pregnancy desires among HIV positive women in Gert Sibande district in Mpumalanga, South Africa
- HIV sero-status disclosure and sexual behaviour among HIV positive patients who are on antiretroviral treatment (ART) in Mpumalanga, South Africa
- Report on PMTCT comprehensive community intervention package including male involvement, infant follow-up, peer support, partner violence and infant feeding in Nkangala district, Mpumalanga province
- Children born into families affected by HIV
- PMTCT implementation in rural community health centres in Mpumalanga province, South Africa: final report
- Prevention of Mother to Child Transmission (PMTCT) implementation in rural community health centres in Mpumalanga Province, South Africa
- Prevention of mother-to-child transmission (PMTCT) implementation in rural community health centres in Mpumalanga province, South Africa
- Prevention of mother to child transmission: a report of an assessment of a pilot programme in fifteen health facilities in Gauteng province
- The costing of a rural PMTCT pilot site in the Eastern Cape
- Factors influencing the utilisation of prevention of mother-to-child-transmission (PMTCT) services by pregnant women in the eastern Cape, South Africa
- An exploratory study of the impact of primary caregiver HIV infection on caregiving and child developmental outcome in the era of Haart: piloting the methodology
- The practicalities of using Nevirapine for PMTCT in under-resourced settings: the case of Qaukeni district in the eastern Cape province, South Africa
- Universal HIV testing of infants at immunization clinics: an acceptable and feasible approach for early infant diagnosis in high HIV prevalence settings
- Prevention of HIV from mother to child (PMTCT) in a resource poor setting in the Eastern Cape, South Africa: baseline survey of pregnant women
- Follow-up survey of women who have undergone PMTCT in a resource poor setting
- Older people as resources in South Africa: Mpumalanga households