The interaction between HIV and intestinal Helminth parasites coinfection with nutrition among adults in KwaZulu-Natal, South Africa

SOURCE: Biomed Research International
OUTPUT TYPE: Journal Article
PUBLICATION YEAR: 2016
TITLE AUTHOR(S): B.T.Mkhize, M.Mabaso, T.Mamba, C.E.Napier, Z.L.Mkhize-Kwitshana
KEYWORDS: ADULTS, GEOHELMINTH INFECTIONS, HIV/AIDS, KWAZULU-NATAL
DEPARTMENT: Social Aspects of Public Health (SAPH)
Print: HSRC Library: shelf number 9711

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Abstract

In South Africa few studies have examined the effects of the overlap of HIV and helminth infections on nutritional status. This cross-sectional study investigated the interaction between HIV and intestinal helminths coinfection with nutritional status among KwaZulu-Natal adults. Participants were recruited from a comprehensive primary health care clinic and stratified based on their HIV, stool parasitology, IgE, and IgG4 results into four groups: the uninfected, HIV infected, helminth infected, and HIV-helminth coinfected groups. The nutritional status was assessed using body mass index, 24-hour food recall, micro-, and macronutrient biochemical markers. Univariate and multivariate multinomial probit regression models were used to assess nutritional factors associated with singly and dually infected groups using the uninfected group as a reference category. Biochemically, the HIVhelminth coinfected group was associated with a significantly higher total protein, higher percentage of transferrin saturation, and significantly lower ferritin. There was no significant association between single or dual infections with HIV and helminths with micro- and macronutrient deficiency; however general obesity and low micronutrient intake patterns, which may indicate a general predisposition to micronutrient and protein-energy deficiency, were observed and may need further investigations.